Liwen Xu

Liwen Xu

Dr. Liwen Xu is a postdoctoral researcher and assistant researcher in multimodal machine learning models and application for cancer immunotherapy

About me

Contact Information

  • Position: Assistant Researcher / Postdoctoral Researcher
  • Institution: College of Computer Science and Electronic Engineering, Hunan University
  • Email: xuliwen@hnu.edu.cn

General Introduction

  1. Dr. Liwen Xu is a postdoctoral researcher and assistant researcher at the College of Information Science and Engineering, Hunan University.
  2. Selected for the Young Elite Scientists Sponsorship Program by CAST (China Association for Science and Technology).
  3. Over the past five years, Liwen Xu has published 10 papers as the first and corresponding author (including co-corresponding) in major international SCI journals such as Nature Communications, Cancer Research, Briefings in Bioinformatics, EBioMedicine, and at the top international conference in bioinformatics, the IEEE International Conference on Bioinformatics and Biomedicine (IEEE BIBM). One of the publications is a highly cited paper according to ESI, with the highest number of citations for a single paper in Google Scholar being 415.
  4. Google Scholar page

Research Interests

  • Multimodal Machine Learning Models and Application for Cancer Immunotherapy
  • Multi-omics analysis
  • single-cell sequencing analysis

Publications

First and Corresponding Author

  1. Liwen Xu#, Chunyu Deng#, Bo Pang#, Xinxin Zhang#, Wei Liu, et al. TIP: A Web Server for Resolving Tumor Immunophenotype Profiling. Cancer Research, 2018 Dec 1（ESI highly cited）
  2. Wenwu Zeng, Yutao Dou, Liangrui Pan, Liwen Xu*, Shaoliang Peng*, Interpretable improving prediction performance of general protein language model by domain-adaptive pretraining on DNA-binding protein. Nature Communications, 2024
  3. Liwen Xu#, Boya Ji, Yijun Peng, Wending Pi, and Shaoliang Peng. ImmRegInformer: an interpretable Transformer-based method for prioritizing immune-regulatory cancer drivers. In 2023 IEEE BIBM（CCF-B）
  4. Liwen Xu#, Shiwei Zhu#, Yujia Lan, Min Yan, Zedong Jiang, et al. Revealing the contribution of somatic gene mutations to shaping tumor immune microenvironment. Briefings in bioinformatics, 2022 Mar 1
  5. Liangrui Pan, Yijun Peng, Yan Li, Xiang Wang, Wenjuan Liu, Liwen Xu*, Qingchun Liang, Shaoliang Peng. SELECTOR: Heterogeneous graph network with convolutional masked autoencoder for multimodal robust prediction of cancer survival. Comput Biol Med, 2024 Apr
  6. Liangrui Pan, Yutao Dou, Zhichao Feng, Liwen Xu*, and Shaoliang Peng*. LDCSF: Local depth convolution-based Swim framework for classifying multi-label histopathology images. In 2023 IEEE BIBM（CCF-B）
  7. Liangrui Pan, Lian Wang, Zhichao Feng, Liwen Xu*, and Shaoliang Peng*. CVFC: Attention-Based Cross-View Feature Consistency for Weakly Supervised Semantic Segmentation of Pathology Images. In 2023 IEEE BIBM（CCF-B）
  8. Jinyuan Xu#, Aiai Shi#, Zhilin Long#, Liwen Xu#, Gaoming Liao, et al. Capturing functional long non-coding RNAs through integrating large-scale causal relations from gene perturbation experiments. EBioMedicine, 2018 Sep
  9. Shangqin Sun#, Liwen Xu#, Xinxin Zhang, Lin Pang, Zhilin Long, et al. Systematic Assessment of Transcriptomic Biomarkers for Immune Checkpoint Blockade Response in Cancer Immunotherapy. Cancers (Basel), 2021 Apr 1

Representative Work

  • TIP: Tracking Tumor Immunophenotype
  • TIP
    • Developed a user-friendly platform for rapid, efficient, and comprehensive analysis of tumor immunophenotypes.
    • Utilized by immunologists and clinical researchers from over 70 countries and regions with over 28,000 cumulative visits.
    • Highlighted by Cancer Research Journal. See

Adjunct Research Positions

  • Secretary-General, Hunan Bioinformatics Society
  • Chairman, Academic Exchange Committee, Hunan Biomedical Engineering Society